According to Comic Book Resources, the current Supergirl series will be coming to an end with Issue #42.
(Keep in mind we are talking about the COMIC BOOK series, not the CW TV series, which was already picked up for another season.)
I don’t know about anyone else, but I think that it’s been difficult to support Supergirl with all that she’s been through. She went through an “angry girl” phase, she’s been a Red Lantern, she’s been branded public enemy number one by her friends and associates, she went on a quest to find out who destroyed Krypton and why, and then she became corrupted with this whole “Year of the Villain” BS. Why should anyone follow her at this point?
Don’t get me wrong, I’d still like to read more of her adventures. But not if this what we’re going to see more of. She needs to be Supergirl, not Angry Girl or Red Lantern Kara Zor-El or “Kara Zor-El of the cursed planet Krypton” or “Kara Zor-El, daughter of Cyborg Superman Zor-El”… and especially not “Supergirl Who Laughs”. Didn’t we get enough of this stupidity with corrupted Mary Marvel followed by Final Crisis Mary Marvel followed by re-corrupted Mary Marvel? Enough already!